Aspirin sensitivity is common, especially in people with asthma or sinus problems. But a true aspirin allergy — in which your immune system overreacts to the drug — is rare. Signs and symptoms of aspirin allergy or sensitivity range from mild to serious and may include: - Hives
- Itchy skin
- Itchy, watery eyes
- Swelling of the lips, tongue or face
- Breathing difficulty or wheezing
These signs and symptoms usually occur within a few hours of taking the medication.