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Novartis, SkyePharma receive FDA approval for asthma spray Foradil

novartis BASEL (AFX) - Novartis (nyse: NVS) AG and joint venture partner SkyePharma PLC (nasdaq: SKYE) have received market approval for their asthma spray Foradil Certihaler from the US Food and Drug Administration (FDA), following modifications to the product.

The product was recalled in Germany and Switzerland early this year on concern the inhaler was delivering variable doses of the drug.

SkyePharma has since been modifying the device and resubmitted it with the US regulator.

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December 16, 2006

Thousands of lives at stake in fight against chronic lung disease

copdPatients with obstructive lung diseases receive only about 55 percent of recommended medical care, according to a study that reflects the increasing health-care challenges of an aging population.

"The quality of care provided to patients with obstructive lung diseases is not as good as it should be or needs to be," said Dr. Richard Mularski, with Kaiser's Portland-based Center for Health Research.

Mularski is lead author of the study, which was published in the December issue of the journal Chest. The RAND Corp. study is part of the largest examination of the quality of American health care ever undertaken.

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Asthma Prevalence High in Children Who Snore

asthmaISLAMABAD - Preschool children who regularly snore are more likely to have asthma and nocturnal cough than those who do not snore, according to the results of a study published in the August issue of Chest.

Dr. Jennifer K. Peat, of the University of Sydney, Australia, and colleagues measured the prevalence of habitual snoring and other respiratory conditions in preschool children between the ages of two and five years old. Nine hundred seventy-four children were included in the study.

Fifty-four of 516 boys (10.5%) and 48 of 458 girls (10.5%) were snorers on at least four nights per week. No association between snoring and age was observed.

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Rhinoviruses Fatal to Lung Transplant Recipients

researchGENEVA, Switzerland, Dec. 15 -- A common cold virus can be deadly for lung-transplant recipients, reported researchers here.

Two of 11 recipients infected with human rhinoviruses developed progressive respiratory and graft dysfunction leading to their deaths, reported Laurent Kaiser, M.D., of the University Hospital of Geneva, and colleagues.

The findings flout conventional wisdom holding that human rhinoviruses only infect the upper respiratory tract, the investigators wrote in the second December issue of the American Journal of Respiratory and Critical Care Medicine.

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December 14, 2006

Treatment May Leave You Allergy-Free

allergyRagweed allergies makes millions of us miserable with symptoms from red, watery eyes to excessive sneezing. But now a new treatment could soon leave you allergy-free.

It's ragweed season again and oncology nurse Kim Brandt is just one of 36 million Americans allergic to the wild plant.

Kim Brandt, RN, ragweed allergy sufferer: "I would be sneezing, running, watery eyes, itchy nose and nasal congestion."

Sick of the symptoms, Kim joined a study on a new approach called rush immunotherapy.

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European experts point to diet, allergy link; call for wider research

ga2lenA recent report by the EU-backed Network of Excellence GA2LEN, Global Allergy and Asthma European Network, highlights new suspected linkages between diet and allergies, particularly in children. Experts suggest that there has been a fundamental shift in European diets over the past twenty to forty years exposing children and adults alike to greater risks of allergies. Such findings by the nutrition network are indicators of the fresh research the network can contribute to this complex field.

According to experts, fully one third of children and approximately half of the European population will be allergic to one thing or another by 2015. It is widely accepted that an unfortunate combination of hereditary and environmental factors contribute to the development of allergies and asthma. However, a sharp increase in the number of cases has lead researchers to believe that something more than genetics is at play. 

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December 13, 2006

Childhood Asthma Rise Remains a Puzzle

childhood asthmaNearly one in 10 American children now has asthma, a sharp rise that still has scientists searching for a cause, a CDC report concluded Tuesday.

An estimated 6.5 million children under age 18 (8.9%) are now diagnosed with the disease. The rate has more than doubled since 1980, according to the report.

At the same time, racial disparities show evidence of worsening. While 8% of white children are estimated to have asthma, 19% of Puerto Rican children and 13% of black children have the disease.

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State of Childhood Asthma, United States: 1980-2005

childhood asthmaA new report on childhood asthma released today by the Centers for Disease Control and Prevention (CDC) shows that death rates for asthma among children under age 18 have declined since 1999, while doctor visits for the condition have more than doubled over the past decade.

In 2005, nearly 9 percent of children -- 6.5 million children under age 18 -- were reported to currently have asthma. The percentage of children who had asthma more than doubled between 1980 and 1995, from 3.6 percent to 7.5 percent. In 2001, CDC introduced a more precise measurement of asthma and the five years since then the trend has remained stable at historically high levels.

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